Lists allow you to segment your audience.
Market segmentation is the research that determines how your company divides its customers into smaller groups based on characteristics such as: total amount spent, last visit, and average session duration. These segments can later be used to optimize marketing messaging and campaigns to different customers.
Basically, market segmentation is the practice of dividing your target market into approachable groups. You create subsets of a market based on demographics, needs, priorities, common interests, and other behavioral criteria used to better understand the target audience.
Leverage the understanding of your market segment's product, sales, and marketing strategies. Use segmentation in your marketing communications and you can only expect better response rates and ROI.